Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
flaxseed powder Generic food 10 g/day 90 days 18 0.9 ┬Ámol after 90 days LAMPE 1994
ground flaxseed Food administered
Generic food
10 g/day 7 weeks 31 60 nmol/day after 7 weeks HUTCHINS 2000
high-isoflavone burger Food administered
1 burger/day 17 days 22 105 nmol/day after 17 days ROWLAND 2000
isoflavones from soy protein powder Not applicable 0.11 mg/day 9 days 12 8.9 nmol after 24 hours XU 2000
isoflavones from soy protein powder Not applicable 1 mg/day 9 days 12 10.9 nmol after 24 hours XU 2000
isoflavones from soy protein powder Not applicable 2 mg/day 93 days 18 25.6 nmol after 24 hours XU 2000
isoflavones from soy protein powder Not applicable 0.11 mg/day 93 days 18 25.6 nmol after 24 hours XU 2000
isoflavones from soy protein powder Not applicable 1 mg/day 93 days 18 23.5 nmol after 24 hours XU 2000
isoflavones from soy protein powder Not applicable 2 mg/day 9 days 12 13.9 nmol after 24 hours XU 2000
low-isoflavone burger Food administered
1 burger/day 17 days 21 59 nmol/day after 17 days ROWLAND 2000
soybean pieces Food administered
Generic food
125 g/day 9 days 17 180 nmol after 9 days HUTCHINS 1995_01
tempeh Food administered
Generic food
112 g/day 9 days 17 144 nmol after 9 days HUTCHINS 1995_01
rat studies
7-hydroxymatairesinol Not applicable 25 mg/kg bw Single dose 11 0.07 nmol after 24 hours SMEDS 2004
7-hydroxymatairesinol Not applicable 25 mg/kg bw 10 days 11 0.2 nmol after 24 hours SMEDS 2004
lariciresinol Not applicable 25 mg/kg bw Single dose 11 0.26 nmol after 24 hours SMEDS 2004
lariciresinol Not applicable 25 mg/kg bw 10 days 11 0.21 nmol after 24 hours SMEDS 2004
matairesinol Not applicable 25 mg/kg bw Single dose 7 1.57 nmol after 24 hours SMEDS 2004
matairesinol Not applicable 25 mg/kg bw 10 days 7 0.81 nmol after 24 hours SMEDS 2004
secoisolariciresinol Not applicable 25 mg/kg bw Single dose 11 38.5 nmol after 24 hours SMEDS 2004
secoisolariciresinol Not applicable 25 mg/kg bw 10 days 11 73.4 nmol after 24 hours SMEDS 2004