Showing experiments where 4',4"-O-Dimethylepigallocatechin 3-O-gallate has been detected in biofluids Metabolism
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
[polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
human studies | ||||||||||||
epigallocatechin gallate | Not applicable | 2 mg/kg bw | Single dose | 4 | 2 | 0.01 | 2.8 | 46.9 | MENG 2002 | |||
green tea solids in water |
Food administered |
20 mg/kg bw | Single dose | 4 | 2 | 0.02 | 4.1 | 77.5 | MENG 2002 | |||
mouse studies | ||||||||||||
epigallocatechin gallate | Not applicable | 0.3 % of ad libitum drinking fluid | 0 | 5 | Detected (unquantified) | 36.7 after 3 days | MENG 2002 | |||||
green tea solids in water |
Food administered |
0.6 % of ad libitum drinking fluid | 0 | 5 | Detected (unquantified) | 31 after 3 days | MENG 2002 |