Showing all polyphenol metabolites originating from consumption of dietary polyphenol Procyanidin dimer B2 Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| (-)-Epicatechin | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.5 | 0.25 |
|
BABA 2002 | ||||
| 3'-O-Methylepicatechin | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.5 | 0.15 |
|
BABA 2002 | ||||
| Procyanidin dimer B2 | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.5 | 0.5 |
|
BABA 2002 | ||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| (-)-Epicatechin | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.02 | 12.5 nmol after 18 hours | BABA 2002 | |||||
| 3'-O-Methylepicatechin | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.02 | 12.8 nmol after 18 hours | BABA 2002 | |||||
| Procyanidin dimer B2 | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.34 | 83 nmol after 18 hours | BABA 2002 | |||||