Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Caffeic acid Not applicable 50 µmol/kg bw Single dose 4 0.5 µg after 24 hours MIYAKE 2000
Eriodictyol Not applicable 50 µmol/kg bw Single dose 4 25 µg after 24 hours MIYAKE 2000
75 µmol/kg bw Single dose 5 275 ng/mL after 4 hours MIYAKE 2000
Hesperetin Not applicable 50 µmol/kg bw Single dose 4 20 µg after 24 hours MIYAKE 2000
75 µmol/kg bw Single dose 5 50 ng/mL after 4 hours MIYAKE 2000
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Caffeic acid Not applicable 50 µmol/kg bw Single dose 4 2 µg after 24 hours MIYAKE 2000
75 µmol/kg bw Single dose 5 3.4 ng/mL after 4 hours MIYAKE 2000
Eriodictyol Not applicable 50 µmol/kg bw Single dose 4 90 µg after 24 hours MIYAKE 2000
Hesperetin Not applicable 50 µmol/kg bw Single dose 4 25 µg after 24 hours MIYAKE 2000