Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
2,4-Dihydroxybenzoic acid Not applicable 440 mg/day 7 days 20 16 µmol/24h after 1 weeks OLTHOF 2003
2-Hydroxy-2-phenylacetic acid Not applicable 440 mg/day 7 days 20 6 µmol/24h after 1 weeks OLTHOF 2003
2-Hydroxyhippuric acid Not applicable 440 mg/day 7 days 20 6.2 µmol/24h after 1 weeks OLTHOF 2003
2-Hydroxyphenylacetic acid Not applicable 440 mg/day 7 days 20 8.2 µmol/24h after 1 weeks OLTHOF 2003
3,4-Dihydroxyphenylacetic acid Not applicable 440 mg/day 7 days 20 52 µmol/24h after 1 weeks OLTHOF 2003
3,5-Dihydroxybenzoic acid Not applicable 440 mg/day 7 days 20 47 µmol/24h after 1 weeks OLTHOF 2003
3-Hydroxyphenylacetic acid Not applicable 440 mg/day 7 days 20 259 µmol/24h after 1 weeks OLTHOF 2003
4-Hydroxybenzoic acid Not applicable 440 mg/day 7 days 20 29 µmol/24h after 1 weeks OLTHOF 2003
4-Hydroxyphenylacetic acid Not applicable 440 mg/day 7 days 20 150 µmol/24h after 1 weeks OLTHOF 2003
Benzoic acid Not applicable 440 mg/day 7 days 20 9 µmol/24h after 1 weeks OLTHOF 2003
Ferulic acid Not applicable 440 mg/day 7 days 20 27 µmol/24h after 1 weeks OLTHOF 2003
Hippuric acid Not applicable 440 mg/day 7 days 20 2700 µmol/24h after 1 weeks OLTHOF 2003
Homovanillic acid Not applicable 440 mg/day 7 days 20 103 µmol/24h after 1 weeks OLTHOF 2003
Phenylacetic acid Not applicable 440 mg/day 7 days 20 22 µmol/24h after 1 weeks OLTHOF 2003
Protocatechuic acid Not applicable 440 mg/day 7 days 20 13 µmol/24h after 1 weeks OLTHOF 2003
Sinapic acid Not applicable 440 mg/day 7 days 20 26 µmol/24h after 1 weeks OLTHOF 2003
Syringic acid Not applicable 440 mg/day 7 days 20 8.3 µmol/24h after 1 weeks OLTHOF 2003
Vanillic acid Not applicable 440 mg/day 7 days 20 80 µmol/24h after 1 weeks OLTHOF 2003