Showing all polyphenol metabolites originating from consumption of dietary polyphenol Lariciresinol Metabolism
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
rat studies | ||||||||||||
7-Hydroxyenterolactone | Not applicable | 25 mg/kg bw | Single dose | 11 | 0.36 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 11.2 nmol after 24 hours | SMEDS 2004 | ||||||||
7-Hydroxymatairesinol | Not applicable | 25 mg/kg bw | Single dose | 11 | 2.88 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 3.71 nmol after 24 hours | SMEDS 2004 | ||||||||
Cyclolariciresinol | Not applicable | 25 mg/kg bw | Single dose | 11 | 735 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 863 nmol after 24 hours | SMEDS 2004 | ||||||||
Enterodiol | Not applicable | 25 mg/kg bw | Single dose | 11 | 113 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 11.2 nmol after 24 hours | SMEDS 2004 | ||||||||
Enterolactone | Not applicable | 25 mg/kg bw | Single dose | 11 | 33.2 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 896 nmol after 24 hours | SMEDS 2004 | ||||||||
Lariciresinol | Not applicable | 25 mg/kg bw | Single dose | 11 | 696 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 891 nmol after 24 hours | SMEDS 2004 | ||||||||
Matairesinol | Not applicable | 25 mg/kg bw | Single dose | 11 | 0.26 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 11 | 0.21 nmol after 24 hours | SMEDS 2004 | ||||||||
Secoisolariciresinol | Not applicable | 25 mg/kg bw | Single dose | 11 | 13.9 nmol after 24 hours | SMEDS 2004 | ||||||
25 mg/kg bw | 10 days | 7 | 18.5 nmol after 24 hours | SMEDS 2004 |