Showing all polyphenol metabolites originating from consumption of Orange [Blood], pure juice Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Hesperetin |
Food administered Generic food |
150 mL | Single dose | 7 | 5.3 | 0.14 | 1.1 | 195.5 |
|
GARDANA 2007_02 | ||
| 5 mL/kg bw | Single dose | 16 | 4.06 | 7 | 0.48 | 1.16 |
|
NIELSEN 2006 | ||||
| 300 g | Single dose | 129 | 3.9 | BRETT 2009 | ||||||||
| 300 g | Single dose | 20 | 4.63 | 6.2 | 0.1 | 346 |
|
BRETT 2009 | ||||
| Naringenin |
Food administered Generic food |
150 mL | Single dose | 7 | 5 | 0.06 | 1.3 | 53.9 |
|
GARDANA 2007_02 | ||
| 300 g | Single dose | 129 | 14.5 | BRETT 2009 | ||||||||
| 300 g | Single dose | 20 | 10.2 | 4.46 | 0.05 | 176 |
|
BRETT 2009 | ||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Cyanidin 3-O-(6''-malonyl-glucoside) |
Food administered Generic food |
1 L | Single dose | 6 |
|
VITAGLIONE 2007 | ||||||
| Cyanidin 3-O-glucoside |
Food administered Generic food |
1 L | Single dose | 6 |
|
0.5 | 0 | 7 |
|
VITAGLIONE 2007 | ||
| Protocatechuic acid |
Food administered Generic food |
1 L | Single dose | 6 | 2 | 0.49 | 11 |
|
VITAGLIONE 2007 | |||
| Hesperetin 3'-O-glucuronide | Generic food | 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
| Hesperetin 7-O-glucuronide | Generic food | 300 g | Single dose | 129 | Detected (unquantified) | BRETT 2009 | ||||||
| 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||||
| Naringenin 4'-O-glucuronide | Generic food | 300 g | Single dose | 129 | Detected (unquantified) | BRETT 2009 | ||||||
| 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||||
| Naringenin 7-O-glucuronide | Generic food | 300 g | Single dose | 129 | Detected (unquantified) | BRETT 2009 | ||||||
| 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||||