Showing all polyphenol metabolites originating from consumption of Orange [Blond], pure juice, alpha rhamnosidase-treated Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Naringenin |
Food administered |
0 | Single dose | 16 | 47 | 1.63 | 0.77 | 70 |
|
BREDSDORFF 2010 | ||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Hesperetin 3',7-O-diglucuronide |
Food administered |
0 | Single dose | 16 | Detected (unquantified) | BREDSDORFF 2010 | ||||||
| Hesperetin 3'-O-glucuronide |
Food administered |
0 | Single dose | 16 | 41 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
| Hesperetin 3'-sulfate |
Food administered |
0 | Single dose | 16 | 8 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
| Hesperetin 5,7-O-diglucuronide |
Food administered |
0 | Single dose | 16 | Detected (unquantified) | BREDSDORFF 2010 | ||||||
| Hesperetin 7-O-glucuronide |
Food administered |
0 | Single dose | 16 | 12 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
| Naringenin 4'-O-glucuronide |
Food administered |
0 | Single dose | 16 | 1.5 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
| Naringenin 7-O-glucuronide |
Food administered |
0 | Single dose | 16 | 1.8 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||