Showing all polyphenol metabolites originating from consumption of Tea [black], solids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 2,4-Dihydroxybenzoic acid |
Food administered |
4 g/day | 7 days | 20 | 15 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 2-Hydroxy-2-phenylacetic acid |
Food administered |
4 g/day | 7 days | 20 | 7 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 2-Hydroxyhippuric acid |
Food administered |
4 g/day | 7 days | 20 | 9.7 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 2-Hydroxyphenylacetic acid |
Food administered |
4 g/day | 7 days | 20 | 6.5 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 3,4-Dihydroxyphenylacetic acid |
Food administered |
4 g/day | 7 days | 20 | 26 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 3,5-Dihydroxybenzoic acid |
Food administered |
4 g/day | 7 days | 20 | 48 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 3-Hydroxybenzoic acid |
Food administered |
4 g/day | 7 days | 20 | 68 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 3-Hydroxyphenylacetic acid |
Food administered |
4 g/day | 7 days | 20 | 68 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 4-Hydroxybenzoic acid |
Food administered |
4 g/day | 7 days | 20 | 27 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| 4-Hydroxyphenylacetic acid |
Food administered |
4 g/day | 7 days | 20 | 170 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Benzoic acid |
Food administered |
4 g/day | 7 days | 20 | 8 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Ferulic acid |
Food administered |
4 g/day | 7 days | 20 | 34 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Gallic acid |
Food administered |
4 g/day | 7 days | 20 | 7 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Hippuric acid |
Food administered |
4 g/day | 7 days | 20 | 4400 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Homovanillic acid |
Food administered |
4 g/day | 7 days | 20 | 54 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Phenylacetic acid |
Food administered |
4 g/day | 7 days | 20 | 21 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Protocatechuic acid |
Food administered |
4 g/day | 7 days | 20 | 12 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Syringic acid |
Food administered |
4 g/day | 7 days | 20 | 6.2 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Vanillic acid |
Food administered |
4 g/day | 7 days | 20 | 69 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Hippuric acid |
Food administered |
6 g | Single dose | 17 | 3.75 mmol after 4 days | MULDER 2005 | ||||||