Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Naringenin Food administered
Generic food
0 Single dose 16 7 5.18 0.12 18 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BREDSDORFF 2010
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Hesperetin 3',7-O-diglucuronide Food administered
Generic food
0 Single dose 16 Detected (unquantified) BREDSDORFF 2010
Hesperetin 3'-O-glucuronide Food administered
Generic food
0 Single dose 16 7 µmol/L after 7.5 hours BREDSDORFF 2010
Hesperetin 3'-sulfate Food administered
Generic food
0 Single dose 16 1 µmol/L after 7.5 hours BREDSDORFF 2010
Hesperetin 5,7-O-diglucuronide Food administered
Generic food
0 Single dose 16 Detected (unquantified) BREDSDORFF 2010
Hesperetin 7-O-glucuronide Food administered
Generic food
0 Single dose 16 2 µmol/L after 7.5 hours BREDSDORFF 2010
Naringenin 4'-O-glucuronide Food administered
Generic food
0 Single dose 16 0.48 µmol/L after 7.5 hours BREDSDORFF 2010
Naringenin 7-O-glucuronide Food administered
Generic food
0 Single dose 16 0.2 µmol/L after 7.5 hours BREDSDORFF 2010