Showing all polyphenol metabolites originating from consumption of Olive, oil, extra virgin Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Homovanillyl alcohol |
Food administered Generic food |
30 mL | Single dose | 6 | VISIOLI 2003 | |||||||
| Hydroxytyrosol |
Food administered Generic food |
30 mL | Single dose | 6 | VISIOLI 2003 | |||||||
| rat studies | ||||||||||||
| Homovanillyl alcohol | Generic food | 1.1 g/kg bw/day | 80 days | 3 | 53.5 ng/mL after 80 days | BAZOTI 2009 | ||||||
| 500 µL | Single dose | 6 |
|
VISIOLI 2003 | ||||||||
| Hydroxytyrosol |
Food administered Generic food |
50 g/kg bw/day | 80 days | 1 | 404.3 ng/mL after 80 days | BAZOTI 2005 | ||||||
| 500 µL | Single dose | 6 |
|
VISIOLI 2003 | ||||||||
| Oleuropein | Generic food | 1.1 g/kg bw/day | 80 days | 3 | Trace amount | BAZOTI 2009 | ||||||
| Tyrosol |
Food administered Generic food |
50 g/kg bw/day | 80 days | 1 | 1855.6 ng/mL after 80 days | BAZOTI 2005 | ||||||