Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Homovanillyl alcohol Food administered
Generic food
30 mL Single dose 6 VISIOLI 2003
Hydroxytyrosol Food administered
Generic food
30 mL Single dose 6 VISIOLI 2003
rat studies
Homovanillyl alcohol Generic food 1.1 g/kg bw/day 80 days 3 53.5 ng/mL after 80 days BAZOTI 2009
500 µL Single dose 6 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VISIOLI 2003
Hydroxytyrosol Food administered
Generic food
50 g/kg bw/day 80 days 1 404.3 ng/mL after 80 days BAZOTI 2005
500 µL Single dose 6 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VISIOLI 2003
Oleuropein Generic food 1.1 g/kg bw/day 80 days 3 Trace amount BAZOTI 2009
Tyrosol Food administered
Generic food
50 g/kg bw/day 80 days 1 1855.6 ng/mL after 80 days BAZOTI 2005