Showing experiments where Urolithin A has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| pomegranate juice concentrate |
Food administered Generic food |
180 mL | Single dose | 18 |
|
SEERAM 2006_02 | ||||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| pomegranate extract capsules |
Food administered |
800 g | Single dose | 11 | Detected (unquantified) | MERTENS-TALCOTT 2006 | ||||||
| pomegranate juice |
Food administered Generic food |
1 L/day | 5 days | 6 | 0.01 g after 6 days | CERDA 2004 | ||||||
| rat studies | ||||||||||||
| punicalagins | Not applicable | 6 % of diet | 37 days | 5 |
|
CERDA 2003_01 | ||||||
| mouse studies | ||||||||||||
| urolithin A | Not applicable | 0.3 mg | Single dose | 72 |
|
SEERAM 2007 | ||||||
| pig studies | ||||||||||||
| acorns from Quercus ilex and Quercus suber |
Food administered |
4.04 kg/day | 117 days | 16 | Detected (unquantified) | ESPIN 2007 | ||||||