Showing experiments where Oleuropein has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| extra virgin olive oil | Generic food | 1.1 g/kg bw/day | 80 days | 3 | Trace amount | BAZOTI 2009 | ||||||
| oleuropein | Not applicable | 0.33 mg/kg bw/day | 80 days | 3 | Trace amount | BAZOTI 2009 | ||||||
| oleuropein in soya oil and water | Not applicable | 100 mg/kg bw | Single dose | 3 | 95 ng/mL after 24 hours | 2 | 0.37 |
|
DEL BOCCIO 2003 | |||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| oleuropein in soya oil and water | Not applicable | 100 mg/kg bw | Single dose | 3 | 10 ng/mL after 24 hours | DEL BOCCIO 2003 | ||||||