Showing experiments where 5-(3',4',5'-trihydroxyphenyl)-γ-valerolactone has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| epigallocatechin | Not applicable | 200 mg | Single dose | 4 |
|
MENG 2002 | ||||||
| epigallocatechin gallate | Not applicable | 200 mg | Single dose | 4 |
|
MENG 2002 | ||||||
| green tea powder in hot water |
Food administered |
20 mg/kg bw | Single dose | 5 |
|
|
LI 2000 | |||||
| green tea powder in hot water |
Food administered |
1.2 g | Single dose | 5 |
|
LI 2000 | ||||||
| green tea powder in hot water |
Food administered |
2.4 g | Single dose | 1 | 524.34 µmol after 6 days | LI 2000 | ||||||
| green tea solids in water |
Food administered |
20 mg/kg bw | Single dose | 4 | Detected (unquantified) | Detected (unquantified) | MENG 2002 | |||||
| mouse studies | ||||||||||||
| epigallocatechin gallate | Not applicable | 0.3 % of ad libitum drinking fluid | 0 | 5 | Trace amount | MENG 2002 | ||||||
| green tea solids in water |
Food administered |
0.6 % of ad libitum drinking fluid | 0 | 5 | Detected (unquantified) | MENG 2002 | ||||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| green tea |
Food administered Generic food |
300 mL | Single dose | 5 |
|
ROOWI 2010 | ||||||
| reconstituted green tea | Not applicable | 3 g | Single dose | 3 | Detected (unquantified) | SANG 2008_01 | ||||||