Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Enterodiol Not applicable 25 mg/kg bw Single dose 6 1.32 µg after 24 hours SAARINEN 2002
2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
Enterolactone Not applicable 25 mg/kg bw Single dose 6 17 24.5 µg after 24 hours SAARINEN 2002
2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
Secoisolariciresinol Not applicable 25 mg/kg bw Single dose 6 1.65 µg after 24 hours SAARINEN 2002
2'-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
2-Hydroxyenterodiol Not applicable 2 mg Single dose 2 Trace amount NIEMEYER 2000
2-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
4'-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
4-Hydroxyenterodiol Not applicable 2 mg Single dose 2 Trace amount NIEMEYER 2000
4-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
5-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
6'-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
6-Hydroxyenterolactone Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
Daidzein Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000
Equol Not applicable 2 mg Single dose 2 Detected (unquantified) NIEMEYER 2000