Showing all polyphenol metabolites originating from consumption of dietary polyphenol Enterolactone Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| Enterodiol | Not applicable | 25 mg/kg bw | Single dose | 6 | 1.32 µg after 24 hours | SAARINEN 2002 | ||||||
| 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||||
| Enterolactone | Not applicable | 25 mg/kg bw | Single dose | 6 | 17 | 24.5 µg after 24 hours | SAARINEN 2002 | |||||
| 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||||
| Secoisolariciresinol | Not applicable | 25 mg/kg bw | Single dose | 6 | 1.65 µg after 24 hours | SAARINEN 2002 | ||||||
| 2'-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| 2-Hydroxyenterodiol | Not applicable | 2 mg | Single dose | 2 | Trace amount | NIEMEYER 2000 | ||||||
| 2-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| 4'-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| 4-Hydroxyenterodiol | Not applicable | 2 mg | Single dose | 2 | Trace amount | NIEMEYER 2000 | ||||||
| 4-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| 5-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| 6'-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| 6-Hydroxyenterolactone | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| Daidzein | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||
| Equol | Not applicable | 2 mg | Single dose | 2 | Detected (unquantified) | NIEMEYER 2000 | ||||||