Showing all polyphenol metabolites originating from consumption of dietary polyphenol Daidzein Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 3'-Hydroxydaidzein | Not applicable | 1 capsule | Single dose | 7 | 0.07 µmol after 24 hours | 7.9 | 0.03 | 5.5 | 336.1 |
|
RUFER 2008 | |
| 6,7,4'-Trihydroxyisoflavone | Not applicable | 1 capsule | Single dose | 7 | 0.27 µmol after 24 hours | 7.8 | 0.01 | 5.3 | 113.9 |
|
RUFER 2008 | |
| 7,8,4'-Trihydroxyisoflavone | Not applicable | 1 capsule | Single dose | 7 | 0.03 µmol after 24 hours | 9.6 | 0.01 | 4.9 | 98.5 |
|
RUFER 2008 | |
| Daidzein | Not applicable | 1 capsule | Single dose | 7 | 11.6 |
|
8.3 | 0.43 | 10.9 | 8.3 |
|
RUFER 2008 |
| Dihydrodaidzein | Not applicable | 1 capsule | Single dose | 7 | 9.11 µmol after 24 hours | 9.1 | 0.14 | 10.9 | 2.4 |
|
RUFER 2008 | |
| Equol | Not applicable | 1 capsule | Single dose | 7 | 7.63 µmol after 24 hours | 24 | 0.36 | 2.5 | 7.7 |
|
RUFER 2008 | |
| O-Desmethylangolensin | Not applicable | 1 capsule | Single dose | 7 | 1.23 µmol after 24 hours | 27.4 | 0.03 | 17.7 | 1.9 |
|
RUFER 2008 | |
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| Daidzein | Not applicable | 100 mg/kg bw | Single dose | 8 |
|
BAYER 2001 | ||||||