Showing all polyphenol metabolites originating from consumption of dietary polyphenol Trans-Resveratrol Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Resveratrol | Not applicable | 1 mg/kg | Single dose | 1 | 26 |
|
0.75 µg/mL after 1.5 hours | MENG 2004 | ||||
| 0.5 mg/kg | Single dose | 1 | 34 | MENG 2004 | ||||||||
| 0.03 mg/kg | Single dose | 1 | 52 |
|
MENG 2004 | |||||||
| Trans-Resveratrol | Not applicable | 25 mg | Single dose | 10 |
|
|
SOLEAS 2001 | |||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Resveratrol | Not applicable | 1 g | Single dose | 4 | Detected (unquantified) | 1.5 | 1 |
|
BOOCOCK 2007_02 | |||
| Trans-Resveratrol | Not applicable | 25 mg | Single dose | 10 |
|
|
SOLEAS 2001 | |||||
| rat studies | ||||||||||||
| Trans-Resveratrol | Not applicable | 20 mg/kg bw | Single dose | 25 |
|
ASENSI 2002 | ||||||
| mouse studies | ||||||||||||
| Trans-Resveratrol | Not applicable | 20 mg/kg bw | Single dose | 25 |
|
ASENSI 2002 | ||||||
| rabbit studies | ||||||||||||
| Trans-Resveratrol | Not applicable | 20 mg/kg bw | Single dose | 5 |
|
ASENSI 2002 | ||||||