Showing all polyphenol metabolites originating from consumption of dietary polyphenol Secoisolariciresinol Metabolism

  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered		 Dose
duration		 Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
7-Hydroxyenterolactone Not applicable 25 mg/kg bw Single dose 11 1.34 nmol after 24 hours SMEDS 2004
25 mg/kg bw 10 days 11 15.1 nmol after 24 hours SMEDS 2004
7-Hydroxymatairesinol Not applicable 25 mg/kg bw Single dose 11 1.71 nmol after 24 hours SMEDS 2004
25 mg/kg bw Single dose 6 62.7 µg after 24 hours SAARINEN 2002
25 mg/kg bw 10 days 11 0.72 nmol after 24 hours SMEDS 2004
Cyclolariciresinol Not applicable 25 mg/kg bw Single dose 11 1.39 nmol after 24 hours SMEDS 2004
25 mg/kg bw 10 days 11 1.19 nmol after 24 hours SMEDS 2004
Enterodiol Not applicable 25 mg/kg bw Single dose 11 1.23 nmol after 24 hours SMEDS 2004
25 mg/kg bw Single dose 6 46.2 µg after 24 hours SAARINEN 2002
25 mg/kg bw 10 days 11 5.85 nmol after 24 hours SMEDS 2004
Enterolactone Not applicable 25 mg/kg bw Single dose 11 137 nmol after 24 hours SMEDS 2004
25 mg/kg bw Single dose 6 58 40.9 µg after 24 hours SAARINEN 2002
25 mg/kg bw 10 days 11 1328 nmol after 24 hours SMEDS 2004
Lariciresinol Not applicable 25 mg/kg bw Single dose 11 0.55 nmol after 24 hours SMEDS 2004
25 mg/kg bw 10 days 11 0.5 nmol after 24 hours SMEDS 2004
Matairesinol Not applicable 25 mg/kg bw Single dose 11 38.5 nmol after 24 hours SMEDS 2004
25 mg/kg bw 10 days 11 73.4 nmol after 24 hours SMEDS 2004
Secoisolariciresinol Not applicable 25 mg/kg bw Single dose 6 6.31 µg after 24 hours SAARINEN 2002