Showing all polyphenol metabolites originating from consumption of dietary polyphenol Matairesinol Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| 7-Hydroxyenterolactone | Not applicable | 25 mg/kg bw | Single dose | 7 | 63.4 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | 10 days | 7 | 72.6 nmol after 24 hours | SMEDS 2004 | ||||||||
| 7-Hydroxymatairesinol | Not applicable | 25 mg/kg bw | Single dose | 7 | 553 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | 10 days | 7 | 725 nmol after 24 hours | SMEDS 2004 | ||||||||
| Cyclolariciresinol | Not applicable | 25 mg/kg bw | Single dose | 7 | 1.89 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | 10 days | 7 | 2.8 nmol after 24 hours | SMEDS 2004 | ||||||||
| Enterodiol | Not applicable | 25 mg/kg bw | Single dose | 7 | 0.57 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | Single dose | 6 | 1.03 µg after 24 hours | SAARINEN 2002 | ||||||||
| 25 mg/kg bw | 10 days | 7 | 13.4 nmol after 24 hours | SMEDS 2004 | ||||||||
| Enterolactone | Not applicable | 25 mg/kg bw | Single dose | 7 | 50 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | Single dose | 6 | 76 | 54.7 µg after 24 hours | SAARINEN 2002 | |||||||
| 25 mg/kg bw | 10 days | 7 | 950 nmol after 24 hours | SMEDS 2004 | ||||||||
| Lariciresinol | Not applicable | 25 mg/kg bw | Single dose | 7 | 1.08 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | 10 days | 7 | 2.22 nmol after 24 hours | SMEDS 2004 | ||||||||
| Matairesinol | Not applicable | 25 mg/kg bw | Single dose | 7 | 1.57 nmol after 24 hours | SMEDS 2004 | ||||||
| 25 mg/kg bw | 10 days | 7 | 0.81 nmol after 24 hours | SMEDS 2004 | ||||||||