Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Enterodiol Not applicable 3.7 kBq/g bw Single dose 12 60 RICKARD 2000
25 mg/kg bw Single dose 6 1.93 µg after 24 hours SAARINEN 2002
1.5 mg/day 10 days 12 50 RICKARD 2000
Enterolactone Not applicable 3.7 kBq/g bw Single dose 12 6 RICKARD 2000
25 mg/kg bw Single dose 6 311 µg after 24 hours SAARINEN 2002
1.5 mg/day 10 days 12 9.5 RICKARD 2000
Secoisolariciresinol Not applicable 3.7 kBq/g bw Single dose 12 14 RICKARD 2000
1.5 mg/day 10 days 12 16 RICKARD 2000