Showing all polyphenol metabolites originating from consumption of dietary polyphenol Secoisolariciresinol di-O-glucoside Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| Enterodiol | Not applicable | 3.7 kBq/g bw | Single dose | 12 | 60 | RICKARD 2000 | ||||||
| 25 mg/kg bw | Single dose | 6 | 1.93 µg after 24 hours | SAARINEN 2002 | ||||||||
| 1.5 mg/day | 10 days | 12 | 50 | RICKARD 2000 | ||||||||
| Enterolactone | Not applicable | 3.7 kBq/g bw | Single dose | 12 | 6 | RICKARD 2000 | ||||||
| 25 mg/kg bw | Single dose | 6 | 311 µg after 24 hours | SAARINEN 2002 | ||||||||
| 1.5 mg/day | 10 days | 12 | 9.5 | RICKARD 2000 | ||||||||
| Secoisolariciresinol | Not applicable | 3.7 kBq/g bw | Single dose | 12 | 14 | RICKARD 2000 | ||||||
| 1.5 mg/day | 10 days | 12 | 16 | RICKARD 2000 | ||||||||