Showing all polyphenol metabolites originating from consumption of Chow containing 10% natural cocoa Metabolism

  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered		 Dose
duration		 Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
(-)-Epicatechin Food administered
 10 % of diet 2 weeks 7 36.62 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
3,4-Dihydroxyphenylacetic acid Food administered
 10 % of diet 2 weeks 7 0.4 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
3-Hydroxybenzoic acid Food administered
 10 % of diet 2 weeks 7 7.2 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
3-Hydroxyphenylacetic acid Food administered
 10 % of diet 2 weeks 7 181.56 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
4-Hydroxybenzoic acid Food administered
 10 % of diet 2 weeks 7 10.28 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Caffeic acid Food administered
 10 % of diet 2 weeks 7 1.26 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Dihydrocaffeic acid Food administered
 10 % of diet 2 weeks 7 0.93 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Enterodiol Food administered
 10 % of diet 2 weeks 7 0.004 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Enterolactone Food administered
 10 % of diet 2 weeks 7 2.05 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Hippuric acid Food administered
 10 % of diet 2 weeks 7 75.34 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Homovanillic acid Food administered
 10 % of diet 2 weeks 7 11.27 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
m-Coumaric acid Food administered
 10 % of diet 2 weeks 7 46.13 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
p-Coumaric acid Food administered
 10 % of diet 2 weeks 7 1.73 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Phenylacetic acid Food administered
 10 % of diet 2 weeks 7 20.52 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Procyanidin dimer B2 Food administered
 10 % of diet 2 weeks 7 3.1 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Protocatechuic acid Food administered
 10 % of diet 2 weeks 7 18.84 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
Vanillic acid Food administered
 10 % of diet 2 weeks 7 50.57 nmol/mg creatinine after 14 days URPI-SARDA 2009_01