Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Homovanillyl alcohol Food administered
Generic food
25 mL Single dose 6 122.9 µg after 12 hours 0.88 0.01 10.43 MIRO-CASAS 2003
Hydroxytyrosol Food administered
Generic food
50 mL Single dose 11 MIRO-CASAS 2001
25 mL Single dose 6 479.6 µg after 12 hours 0.58 0.11 46.82 MIRO-CASAS 2003
Tyrosol Food administered
Generic food
50 mL Single dose 11 MIRO-CASAS 2001
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
3,4-DHPEA-EDA Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
4-Hydroxybenzoic acid Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Homovanillic acid 4-sulfate Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Homovanillyl alcohol Food administered
Generic food
25 mL Single dose 6 7.5 µg after 12 hours MIRO-CASAS 2003
Hydroxytyrosol Food administered
Generic food
50 mL Single dose 11 47.3 µg after 24 hours MIRO-CASAS 2001
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
p-HPEA-EDA Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Tyrosol Food administered
Generic food
50 mL Single dose 11 28.6 µg after 24 hours MIRO-CASAS 2001
Tyrosol 4-sulfate Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Vanillic acid Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Vanillic acid 4-sulfate Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Vanillin Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009
Vanillin 4-sulfate Food administered
Generic food
30 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 SUAREZ 2009