Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
olive oil sample A Not applicable 50 mL Single dose 6 21 375 µg after 24 hours VISIOLI 2000_01
olive oil sample B Not applicable 50 mL Single dose 6 28 1200 µg after 24 hours VISIOLI 2000_01
olive oil sample C Not applicable 50 mL Single dose 6 21 1100 µg after 24 hours VISIOLI 2000_01
olive oil sample D Not applicable 50 mL Single dose 6 24 1600 µg after 24 hours VISIOLI 2000_01
virgin olive oil Food administered
Generic food
50 mL Single dose 11 MIRO-CASAS 2001
rat studies
extra virgin olive oil Food administered
Generic food
50 g/kg bw/day 80 days 1 1855.6 ng/mL after 80 days BAZOTI 2005
oleuropein Not applicable 0.15 g/kg bw/day 80 days 3 814.5 ng/ml after 80 days BAZOTI 2005
  Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
olive oil sample A Not applicable 50 mL Single dose 6 45 µg after 24 hours VISIOLI 2000_01
olive oil sample B Not applicable 50 mL Single dose 6 65 µg after 24 hours VISIOLI 2000_01
olive oil sample C Not applicable 50 mL Single dose 6 95 µg after 24 hours VISIOLI 2000_01
olive oil sample D Not applicable 50 mL Single dose 6 30 µg after 24 hours VISIOLI 2000_01
virgin olive oil Food administered
Generic food
50 mL Single dose 11 28.6 µg after 24 hours MIRO-CASAS 2001