Showing experiments where Hesperetin 3'-O-glucuronide has been detected in biofluids Metabolism
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
[polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
human studies | ||||||||||||
alpha-rhamnosidase treated orange juice |
Food administered |
0 | Single dose | 16 | 41 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
fresh orange segments |
Food administered Generic food |
150 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
hesperidin-fortified orange juice |
Food administered |
0 | Single dose | 16 | 49 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
orange juice |
Food administered Generic food |
0 | Single dose | 16 | 7 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
orange juice | Generic food | 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
rat studies | ||||||||||||
hesperidin | Not applicable | 50 mg/kg bw | Single dose | 5 | Detected (unquantified) | MATSUMOTO 2004 |