Showing experiments where Hesperetin 7-O-glucuronide has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| alpha-rhamnosidase treated orange juice |
Food administered |
0 | Single dose | 16 | 12 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
| fresh orange segments |
Food administered Generic food |
150 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
| hesperidin-fortified orange juice |
Food administered |
0 | Single dose | 16 | 5 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
| orange juice |
Food administered Generic food |
0 | Single dose | 16 | 2 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
| orange juice | Generic food | 300 g | Single dose | 129 | Detected (unquantified) | BRETT 2009 | ||||||
| orange juice | Generic food | 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
| polyphenol-rich beverage |
Food administered |
350 mL | Single dose | 10 |
|
BORGES 2010 | ||||||
| polyphenol-rich juice drink |
Food administered |
350 mL | Single dose | 10 | Detected (unquantified) | MULLEN 2010 | ||||||
| rat studies | ||||||||||||
| hesperidin | Not applicable | 50 mg/kg bw | Single dose | 5 | Detected (unquantified) |
|
MATSUMOTO 2004 | |||||