Showing experiments where Naringenin 7-O-glucuronide has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| alpha-rhamnosidase treated orange juice |
Food administered |
0 | Single dose | 16 | 1.8 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
| fresh orange segments |
Food administered Generic food |
150 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
| grapefruit juice |
Food administered |
900 mL | Single dose | 1 | Detected (unquantified) | DAVIS 2006 | ||||||
| hesperidin-fortified orange juice |
Food administered |
0 | Single dose | 16 | 0.2 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
| orange juice |
Food administered Generic food |
0 | Single dose | 16 | 0.2 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
| orange juice | Generic food | 300 g | Single dose | 129 | Detected (unquantified) | BRETT 2009 | ||||||
| orange juice | Generic food | 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
| orange juice fortified with hesperidin | Not applicable | 250 mL | Single dose | 8 | 8.5 |
|
Detected (unquantified) | MULLEN 2008_01 | ||||
| orange juice fortified with hesperidin with 150 mL natural yoghurt | Not applicable | 250 mL | Single dose | 8 | 6.6 |
|
Detected (unquantified) | MULLEN 2008_01 | ||||
| rat studies | ||||||||||||
| naringenin | Not applicable | 50 mg/kg bw | Single dose | 6 | Detected (unquantified) | EL MOHSEN 2004 | ||||||