Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Naringenin Not applicable 270 mg/kg bw Single dose 10 2 161.25 10.51 463107.43 Graph MA 2006
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Dihydro-p-coumaric acid Not applicable 50 mg/kg bw Single dose 8 EL MOHSEN 2004
Naringenin Not applicable 50 mg/kg bw Single dose 6 0.88 ┬Ámol after 18 hours 0.05 nmol/mL after 18 hours EL MOHSEN 2004
270 mg/kg bw Single dose 10 7.94 16.25 7.94 21893.46 Graph MA 2006
Naringenin 5-O-glucuronide Not applicable 50 mg/kg bw Single dose 6 Detected (unquantified) EL MOHSEN 2004
Naringenin 7-O-glucuronide Not applicable 50 mg/kg bw Single dose 6 Detected (unquantified) EL MOHSEN 2004