Showing all polyphenol metabolites originating from consumption of dietary polyphenol Naringenin Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| Naringenin | Not applicable | 270 mg/kg bw | Single dose | 10 | 2 | 161.25 | 10.51 | 463107.43 |
|
MA 2006 | ||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| Dihydro-p-coumaric acid | Not applicable | 50 mg/kg bw | Single dose | 8 | EL MOHSEN 2004 | |||||||
| Naringenin | Not applicable | 50 mg/kg bw | Single dose | 6 | 0.88 µmol after 18 hours | 0.05 nmol/mL after 18 hours | EL MOHSEN 2004 | |||||
| 270 mg/kg bw | Single dose | 10 | 7.94 | 16.25 | 7.94 | 21893.46 |
|
MA 2006 | ||||
| Naringenin 5-O-glucuronide | Not applicable | 50 mg/kg bw | Single dose | 6 | Detected (unquantified) | EL MOHSEN 2004 | ||||||
| Naringenin 7-O-glucuronide | Not applicable | 50 mg/kg bw | Single dose | 6 | Detected (unquantified) | EL MOHSEN 2004 | ||||||