Showing all polyphenol metabolites originating from consumption of dietary polyphenol Rosmarinic acid Metabolism
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
rat studies | ||||||||||||
3-O-Methylrosmarinic acid | Not applicable | 50 mg/kg bw | Single dose | 5 | 1 | 5.03 | BABA 2004 | |||||
Caffeic acid | Not applicable | 50 mg/kg bw | Single dose | 5 | 1.06 | BABA 2004 | ||||||
Ferulic acid | Not applicable | 50 mg/kg bw | Single dose | 5 | 1.7 | BABA 2004 | ||||||
m-Coumaric acid | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.67 | 8 | 0.75 | BABA 2004 | ||||
Rosmarinic acid | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.44 | 0.5 | 4.63 | BABA 2004 |
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
rat studies | ||||||||||||
Rosmarinic acid | Not applicable | 50 mg/kg bw | Single dose | 5 | BABA 2004 |