Showing all polyphenol metabolites originating from consumption of Perilla frutescens tablet Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 3-O-Methylrosmarinic acid |
Food administered |
1 tablet | Single dose | 6 | 2.86 |
|
2 | 0.65 | BABA 2005 | |||
| Caffeic acid |
Food administered |
1 tablet | Single dose | 6 | 0.96 |
|
Detected (unquantified) | BABA 2005 | ||||
| Ferulic acid |
Food administered |
1 tablet | Single dose | 6 | 2.86 |
|
BABA 2005 | |||||
| m-Coumaric acid |
Food administered |
1 tablet | Single dose | 6 | Trace amount | Detected (unquantified) | BABA 2005 | |||||
| Rosmarinic acid |
Food administered |
1 tablet | Single dose | 6 | 1.5 |
|
0.5 | 1.15 | BABA 2005 | |||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 3-O-Methylrosmarinic acid |
Food administered |
1 tablet | Single dose | 6 |
|
BABA 2005 | ||||||
| Ferulic acid |
Food administered |
1 tablet | Single dose | 6 | 0.5 | 0.36 | BABA 2005 | |||||
| Rosmarinic acid |
Food administered |
1 tablet | Single dose | 6 |
|
BABA 2005 | ||||||