Showing experiments where Isorhamnetin has been detected in biofluids Metabolism
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
[polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
human studies | ||||||||||||
fried onions |
Food administered |
200 g | Single dose | 4 | 0.11 µmol/L after 1.5 hours | DAY 2001 | ||||||
grape juice preparation |
Food administered |
1200 mL | Single dose | 1 | Detected (unquantified) | MENG 2004 | ||||||
grapefruit juice |
Food administered |
430 mL | Single dose | 9 | 0.1 µmol after 12 hours | ITO 2005 | ||||||
orange juice |
Food administered |
550 g | Single dose | 9 | 0.3 µmol after 12 hours | ITO 2005 | ||||||
quercetin | Not applicable | 0.5 mg/kg bw | Single dose | 2 | Detected (unquantified) | MENG 2004 | ||||||
rat studies | ||||||||||||
isorhamnetin | Not applicable | 0.25 mg/kg bw | Single dose | 10 | 8 | 0.18 | 8.2 | 862.6 | LAN 2007 |
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
[polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
rat studies | ||||||||||||
[2-14C]quercetin 4'-glucoside | Not applicable | 3.26 mg/kg bw | Single dose | 12 | Detected (unquantified) | GRAF 2005 |