Showing experiments where Rosmarinic acid has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| one tablet of perilla extract |
Food administered |
1 tablet | Single dose | 6 | 1.5 |
|
0.5 | 1.15 | BABA 2005 | |||
| rat studies | ||||||||||||
| rosmarinic acid in deoinized water | Not applicable | 50 mg/kg bw | Single dose | 5 | 0.44 |
|
0.5 | 4.63 | BABA 2004 | |||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| one tablet of perilla extract |
Food administered |
1 tablet | Single dose | 6 |
|
BABA 2005 | ||||||
| rat studies | ||||||||||||
| rosmarinic acid in deoinized water | Not applicable | 50 mg/kg bw | Single dose | 5 |
|
|
BABA 2004 | |||||
| shuangdan granules | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||