Showing experiments where Naringenin 4'-O-glucuronide has been detected in biofluids Metabolism
Urine | Plasma | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
[polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
human studies | ||||||||||||
alpha-rhamnosidase treated orange juice |
Food administered |
0 | Single dose | 16 | 1.5 µmol/L after 2.5 hours | BREDSDORFF 2010 | ||||||
fresh orange segments |
Food administered Generic food |
150 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
grapefruit juice |
Food administered |
900 mL | Single dose | 1 | Detected (unquantified) | DAVIS 2006 | ||||||
hesperidin-fortified orange juice |
Food administered |
0 | Single dose | 16 | 0.3 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
orange juice |
Food administered Generic food |
0 | Single dose | 16 | 0.48 µmol/L after 7.5 hours | BREDSDORFF 2010 | ||||||
orange juice | Generic food | 300 g | Single dose | 129 | Detected (unquantified) | BRETT 2009 | ||||||
orange juice | Generic food | 300 g | Single dose | 20 | Detected (unquantified) | Detected (unquantified) | BRETT 2009 | |||||
orange juice fortified with hesperidin | Not applicable | 250 mL | Single dose | 8 | 0.9 | Detected (unquantified) | MULLEN 2008_01 | |||||
orange juice fortified with hesperidin | Not applicable | 250 mL | Single dose | 8 | 8.3 | MULLEN 2008_01 | ||||||
orange juice fortified with hesperidin with 150 mL natural yoghurt | Not applicable | 250 mL | Single dose | 8 | 0.7 | Detected (unquantified) | MULLEN 2008_01 | |||||
orange juice fortified with hesperidin with 150 mL natural yoghurt | Not applicable | 250 mL | Single dose | 8 | 8.6 | MULLEN 2008_01 |