Showing experiments where 5-(3',4',-dihydroxyphenyl)-γ-valerolactone has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| cocoa powder in skimmed milk |
Food administered Generic food |
40 g/day | 4 weeks | 42 | 34.13 µmol after 24 hours | 0.48 µmol/L after 24 hours | URPI-SARDA 2009_03 | |||||
| epicatechin | Not applicable | 200 mg | Single dose | 4 |
|
MENG 2002 | ||||||
| epigallocatechin | Not applicable | 200 mg | Single dose | 4 |
|
MENG 2002 | ||||||
| epigallocatechin gallate | Not applicable | 200 mg | Single dose | 4 |
|
MENG 2002 | ||||||
| green tea powder in hot water |
Food administered |
20 mg/kg bw | Single dose | 5 |
|
|
LI 2000 | |||||
| green tea powder in hot water |
Food administered |
1.2 g | Single dose | 5 |
|
LI 2000 | ||||||
| green tea powder in hot water |
Food administered |
2.4 g | Single dose | 1 | 153.41 µmol after 6 days | LI 2000 | ||||||
| green tea solids in water |
Food administered |
20 mg/kg bw | Single dose | 4 | Detected (unquantified) | Detected (unquantified) | MENG 2002 | |||||
| rat studies | ||||||||||||
| (-)-epicatechin gallate | Not applicable | 100 mg/kg bw | Single dose | 3 |
|
|
KOHRI 2003 | |||||
| catechin | Not applicable | 0.12 g/100 g bw | Single dose | 8 | Detected (unquantified) | GONTHIER 2003_03 | ||||||
| wine powder |
Food administered |
0.5 g/100 g bw | Single dose | 8 | Detected (unquantified) | GONTHIER 2003_03 | ||||||
| mouse studies | ||||||||||||
| epigallocatechin gallate | Not applicable | 0.3 % of ad libitum drinking fluid | 0 | 5 | Trace amount | MENG 2002 | ||||||
| green tea solids in water |
Food administered |
0.6 % of ad libitum drinking fluid | 0 | 5 | Detected (unquantified) | MENG 2002 | ||||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| reconstituted green tea | Not applicable | 3 g | Single dose | 3 | Detected (unquantified) | SANG 2008_01 | ||||||