Showing all polyphenol metabolites originating from consumption of dietary polyphenol Quercetin Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 1,3,5-Trimethoxybenzene | Not applicable | 200 mg | Single dose | 12 |
|
LOKE 2009 | ||||||
| 3-O-Methylgallic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| 3-Phenylpropionic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| 4-Ethylbenzoic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| 4-Ethylphenol | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| 4-O-Methylgallic acid | Not applicable | 200 mg | Single dose | 12 |
|
LOKE 2009 | ||||||
| Benzoic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| Dihydro-p-coumaric acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| Dihydrocaffeic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| Ferulic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| Gallic acid | Not applicable | 200 mg | Single dose | 12 |
|
LOKE 2009 | ||||||
| Isorhamnetin | Not applicable | 0.5 mg/kg bw | Single dose | 2 | Detected (unquantified) | MENG 2004 | ||||||
| Methoxyphenylacetic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| Protocatechuic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| Quercetin | Not applicable | 0.5 mg/kg bw | Single dose | 2 | 7.6 |
|
Trace amount | MENG 2004 | ||||
| 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||||
| 3 capsules/day | Single dose | 10 | 0.31 | MOON 2008 | ||||||||
| Vanillic acid | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| (+)-Catechin | Not applicable | 25 mg | Single dose | 10 |
|
|
SOLEAS 2001 | |||||
| rat studies | ||||||||||||
| Quercetin | Not applicable | 1 % of diet | 28 days | 12 | 1.5 µmol/L after 28 days | KAWAI 2009 | ||||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Quercetin | Not applicable | 20 mg/100 g diet | Single dose | 12 | 0.03 µmol/L after 21 days | SANTOS 2008 | ||||||
| 3 capsules/day | Single dose | 10 | 1.18 | 3 | 0.05 | 3.47 | 62.5 |
|
MOON 2008 | |||
| (+)-Catechin | Not applicable | 25 mg | Single dose | 10 |
|
|
SOLEAS 2001 | |||||