Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
3'-Hydroxydaidzein Not applicable 1 capsule Single dose 7 0.28 µmol after 24 hours 8.6 0.06 7.1 1050.4 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008
6,7,4'-Trihydroxyisoflavone Not applicable 1 capsule Single dose 7 1.9 µmol after 24 hours 9.1 0.01 4.7 292.2 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008
7,8,4'-Trihydroxyisoflavone Not applicable 1 capsule Single dose 7 0.07 µmol after 24 hours 9.7 0.01 4.6 284.9 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008
Daidzein Not applicable 1 capsule Single dose 7 38.9 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 9.1 2.54 6.4 35.8 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008
Dihydrodaidzein Not applicable 1 capsule Single dose 7 31.42 µmol after 24 hours 10 0.75 8.8 29.8 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008
Equol Not applicable 1 capsule Single dose 7 4.97 µmol after 24 hours 12 0.07 6.9 0.9 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008
O-Desmethylangolensin Not applicable 1 capsule Single dose 7 2.26 µmol after 24 hours 22.3 0.1 11 3.5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 RUFER 2008