Showing all polyphenol metabolites originating from consumption of dietary polyphenol Daidzin Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 3'-Hydroxydaidzein | Not applicable | 1 capsule | Single dose | 7 | 0.28 µmol after 24 hours | 8.6 | 0.06 | 7.1 | 1050.4 |
|
RUFER 2008 | |
| 6,7,4'-Trihydroxyisoflavone | Not applicable | 1 capsule | Single dose | 7 | 1.9 µmol after 24 hours | 9.1 | 0.01 | 4.7 | 292.2 |
|
RUFER 2008 | |
| 7,8,4'-Trihydroxyisoflavone | Not applicable | 1 capsule | Single dose | 7 | 0.07 µmol after 24 hours | 9.7 | 0.01 | 4.6 | 284.9 |
|
RUFER 2008 | |
| Daidzein | Not applicable | 1 capsule | Single dose | 7 | 38.9 |
|
9.1 | 2.54 | 6.4 | 35.8 |
|
RUFER 2008 |
| Dihydrodaidzein | Not applicable | 1 capsule | Single dose | 7 | 31.42 µmol after 24 hours | 10 | 0.75 | 8.8 | 29.8 |
|
RUFER 2008 | |
| Equol | Not applicable | 1 capsule | Single dose | 7 | 4.97 µmol after 24 hours | 12 | 0.07 | 6.9 | 0.9 |
|
RUFER 2008 | |
| O-Desmethylangolensin | Not applicable | 1 capsule | Single dose | 7 | 2.26 µmol after 24 hours | 22.3 | 0.1 | 11 | 3.5 |
|
RUFER 2008 | |