Ferruzzi M.G., Lobo J.K., Janle E.M., Cooper B., Simon J.E., Wu Q.L., Welch C., Ho L., Weaver C., Pasinetti G.M. (2009) Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease. J Alzheimers Dis 18:113-24 PubMed (19625746)

Abbreviation: FERRUZZI 2009

Pubmed ID: 19625746

Metabolism

This publication was used in 3 intervention studies.

Source Metabolite Biofluid Organism
Grape, seed, polyphenol extract Gallic acid plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 4-O-Methylgallic acid plasma rat Pharmacokinetics
Grape, seed, polyphenol extract (+)-Catechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 3'-O-Methylcatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract (-)-Epicatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 3'-O-Methylepicatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract Gallic acid plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 4-O-Methylgallic acid plasma rat Pharmacokinetics
Grape, seed, polyphenol extract (+)-Catechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 3'-O-Methylcatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract (-)-Epicatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 3'-O-Methylepicatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract Gallic acid plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 4-O-Methylgallic acid plasma rat Pharmacokinetics
Grape, seed, polyphenol extract (+)-Catechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 3'-O-Methylcatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract (-)-Epicatechin plasma rat Pharmacokinetics
Grape, seed, polyphenol extract 3'-O-Methylepicatechin plasma rat Pharmacokinetics