Showing experiments where (+)-Catechin has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| cocoa in 300 mL water |
Food administered Generic food |
0.37 g/kg bw | Single dose | 5 |
|
HOLT 2002 | ||||||
| dealcoholized red wine |
Food administered |
120 mL | Single dose | 9 | 1.44 | 0.06 | 4.08 | 306 |
|
BELL 2000 | ||
| dealcoholized red wine |
Food administered Generic food |
120 mL | Single dose | 9 | 1.6 | 0.06 | 4.1 | 304 | DONOVAN 1999 | |||
| quercetin in white wine | Not applicable | 25 mg | Single dose | 10 |
|
|
SOLEAS 2001 | |||||
| red wine |
Food administered Generic food |
120 mL | Single dose | 9 | 1.44 | 0.07 | 3.17 | 306 |
|
BELL 2000 | ||
| red wine |
Food administered Generic food |
120 mL | Single dose | 9 | 1.6 | 0.07 | 3.2 | 303 | DONOVAN 1999 | |||
| rat studies | ||||||||||||
| catechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 8.85 µmol after 24 hours | 66.4 |
|
BABA 2001_02 | ||||
| catechin | Not applicable | 0.12 g/100 g bw | Single dose | 8 |
|
1.3 µmol/L after 8 days | GONTHIER 2003_03 | |||||
| catechin | Not applicable | 0.1 % of diet | 5 days | 5 | 37 µmol after 5 days | GONTHIER 2003_02 | ||||||
| grape seed extract in aqueous solution |
Food administered |
600 mg/kg bw/day | 3 days | 8 | Detected (unquantified) | Detected (unquantified) | PRASAIN 2009 | |||||
| grape seed polyphenolic extract |
Food administered |
100 mg/kg bw | Single dose | 8 | 1.8 | 1.34 | 606.1 |
|
FERRUZZI 2009 | |||
| mixture of catechin and epicatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 7.21 µmol after 24 hours | 56.5 |
|
BABA 2001_02 | ||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| quercetin in white wine | Not applicable | 25 mg | Single dose | 10 |
|
|
SOLEAS 2001 | |||||
| rat studies | ||||||||||||
| catechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 1.13 µmol after 24 hours | 0.19 |
|
BABA 2001_02 | ||||
| catechin | Not applicable | 0.2 % of diet | 6 weeks | 8 | Detected (unquantified) | FARDET 2008_01 | ||||||
| mixture of catechin and epicatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 1.05 µmol after 24 hours | 0.15 |
|
BABA 2001_02 | ||||
| procyanidin-rich extract | Not applicable | 1 g/kg bw | Single dose | 3 | 0.85 µmol/L after 2 hours | SERRA 2009 | ||||||