Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
(+)-Catechin Food administered
600 mg/kg bw/day 3 days 8 Detected (unquantified) Detected (unquantified) PRASAIN 2009
100 mg/kg bw Single dose 8 1.8 1.34 606.1 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 FERRUZZI 2009
(-)-Epicatechin Food administered
600 mg/kg bw/day 3 days 8 Detected (unquantified) Detected (unquantified) PRASAIN 2009
100 mg/kg bw Single dose 8 1.5 1.9 1197.9 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 FERRUZZI 2009
3'-O-Methylcatechin Food administered
100 mg/kg bw Single dose 8 1.4 0.24 184.8 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 FERRUZZI 2009
3'-O-Methylepicatechin Food administered
100 mg/kg bw Single dose 8 1.5 0.34 266.6 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 FERRUZZI 2009
4-O-Methylgallic acid Food administered
150 mg/kg bw Single dose 8 0.9 0.4 162.4 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 FERRUZZI 2009
Gallic acid Food administered
100 mg/kg bw Single dose 8 1.3 1.4 673.1 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 FERRUZZI 2009
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
Procyanidin dimer B1 Not applicable 1 g/kg bw Single dose 4 0.5 7.5 µg after 4 hours TSANG 2005
Procyanidin dimer B2 Not applicable 1 g/kg bw Single dose 4 0.3 4.2 µg after 4 hours TSANG 2005
Procyanidin dimer B3 Not applicable 1 g/kg bw Single dose 4 1 6.4 µg after 4 hours TSANG 2005
Procyanidin dimer B4 Not applicable 1 g/kg bw Single dose 4 0.4 3 µg after 4 hours TSANG 2005
Procyanidin trimer C2 Not applicable 1 g/kg bw Single dose 4 4.3 13 µg after 4 hours TSANG 2005