Showing all polyphenol metabolites originating from consumption of Wine [Red] Metabolism

  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered		 Dose
duration		 Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
(+)-Catechin Food administered
Generic food 		120 mL Single dose 9 1.6 0.06 4.1 304 DONOVAN 1999
120 mL Single dose 9 1.44 0.07 3.17 306 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BELL 2000
120 mL Single dose 9 1.6 0.07 3.2 303 DONOVAN 1999
3'-O-Methylcatechin Food administered
Generic food 		120 mL Single dose 9 1.1 0.01 2.4 50 DONOVAN 1999
120 mL Single dose 9 1.2 0.01 2.4 57 DONOVAN 1999
4-O-Methylgallic acid Food administered
Generic food 		5 mL/kg bw Single dose 12 3 0.17 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 CACCETTA 2000
Caffeic acid Food administered
Generic food 		5 mL/kg bw Single dose 12 3 0.08 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 CACCETTA 2000
Protocatechuic acid Food administered
Generic food 		5 mL/kg bw Single dose 12 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 CACCETTA 2000
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered		 Dose
duration		 Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Trans-Resveratrol Food administered
Generic food 		600 mL Single dose 10 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
600 mL Single dose 10 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
600 mL Single dose 5 Detected (unquantified) VITAGLIONE 2005
trans-Resveratrol 3-O-glucuronide Food administered
Generic food 		600 mL Single dose 10 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
600 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
300 mL Single dose 10 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
250 mL Single dose 5 179.2 nmol/g creatinine after 4 hours URPI-SARDA 2007
trans-Resveratrol 4'-O-glucuronide Food administered
Generic food 		600 mL Single dose 10 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
600 mL Single dose 5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
300 mL Single dose 2 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 VITAGLIONE 2005
250 mL Single dose 5 59.6 nmol/g creatinine after 4 hours URPI-SARDA 2007
cis-Resveratrol 3-O-glucuronide Food administered
Generic food 		250 mL Single dose 5 893.5 nmol/g creatinine after 4 hours URPI-SARDA 2007
cis-Resveratrol 3-sulfate Food administered
Generic food 		250 mL Single dose 5 221.2 nmol/g creatinine after 4 hours URPI-SARDA 2007
cis-Resveratrol 4'-O-glucuronide Food administered
Generic food 		250 mL Single dose 5 355.8 nmol/g creatinine after 4 hours URPI-SARDA 2007
cis-Resveratrol 4'-sulfate Food administered
Generic food 		250 mL Single dose 5 9294.2 nmol/g creatinine after 4 hours URPI-SARDA 2007
trans-Resveratrol 3-sulfate Food administered
Generic food 		250 mL Single dose 5 74.7 nmol/g creatinine after 4 hours URPI-SARDA 2007
trans-Resveratrol 4'-sulfate Food administered
Generic food 		250 mL Single dose 5 2.4 nmol/g creatinine after 4 hours URPI-SARDA 2007