Showing experiments where Protocatechuic acid has been detected in biofluids Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| 5-caffeoylquinic acid | Not applicable | 2 g/day | 7 days | 20 | 27 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| almond skin extract capsules |
Food administered |
10 capsules | Single dose | 2 | URPI-SARDA 2009_02 | |||||||
| black tea solids |
Food administered |
4 g/day | 7 days | 20 | 12 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| citric acid in water | Not applicable | 0.5 g/day | 7 days | 20 | 10 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| cocoa powder in skimmed milk |
Food administered Generic food |
40 g/day | 4 weeks | 42 | 34.47 µmol after 24 hours | 10.52 µmol/L after 24 hours | URPI-SARDA 2009_03 | |||||
| cocoa powder in water |
Food administered Generic food |
40 g | Single dose | 21 | 0.51 nmol/mg creatinine after 24 hours | URPI-SARDA 2009_01 | ||||||
| cocoa powder in water |
Food administered Generic food |
40 g | Single dose | 21 |
|
URPI-SARDA 2010 | ||||||
| cocoa powder in whole milk |
Food administered Generic food |
40 g | Single dose | 21 |
|
URPI-SARDA 2010 | ||||||
| dealcoholized red wine equivalents | Not applicable | 5 mL/kg bw | Single dose | 12 |
|
CACCETTA 2000 | ||||||
| epicatechin | Not applicable | 200 mg | Single dose | 12 |
|
LOKE 2009 | ||||||
| epigallocatechin gallate | Not applicable | 200 mg | Single dose | 12 |
|
LOKE 2009 | ||||||
| phenol-stripped red wine equivalents |
Food administered |
5 mL/kg bw | Single dose | 12 |
|
CACCETTA 2000 | ||||||
| quercetin | Not applicable | 200 mg | Single dose | 12 |
|
|
LOKE 2009 | |||||
| quercetin 3-O-rutinoside | Not applicable | 440 mg/day | 7 days | 20 | 13 µmol/24h after 1 weeks | OLTHOF 2003 | ||||||
| red wine equivalents |
Food administered Generic food |
5 mL/kg bw | Single dose | 12 |
|
CACCETTA 2000 | ||||||
| rat studies | ||||||||||||
| catechin | Not applicable | 0.1 % of diet | 5 days | 5 | 0.19 µmol after 5 days | GONTHIER 2003_02 | ||||||
| cranberry powder diet |
Food administered |
6.6 mg/kg bw | Single dose | 10 | 1.03 µg/mg creatinine after 30 days | PRIOR 2010 | ||||||
| natural cocoa |
Food administered |
10 % of diet | 2 weeks | 7 | 18.84 nmol/mg creatinine after 14 days | URPI-SARDA 2009_01 | ||||||
| natural cocoa powder |
Food administered |
4.8 g/kg bw/day | 2 weeks | 7 | 5.66 nmol/mg creatinine after 14 days | URPI-SARDA 2009_01 | ||||||
| procyanidin dimer B3 | Not applicable | 0.1 % of diet | 5 days | 5 | 0.19 µmol after 5 days | GONTHIER 2003_02 | ||||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| [polyphenol] source used in experiment | Source composition | Doses administered | Dose duration | Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| blood orange juice |
Food administered Generic food |
1 L | Single dose | 6 | 2 | 0.49 | 11 |
|
VITAGLIONE 2007 | |||
| rat studies | ||||||||||||
| cranberry powder diet |
Food administered |
6.6 mg/kg bw | Single dose | 10 | 0.26 µg/mg creatinine after 30 days | PRIOR 2010 | ||||||
| cyanidin 3-O-glucoside | Not applicable | 0.9 mmol/kg bw | Single dose | 15 | 1 | 2.56 |
|
TSUDA 1999 | ||||
| wild lowbush blueberry diet | Generic food | 8 % of diet | 8 weeks | 8 |
|
DEL BO 2010 | ||||||