Showing experiments where Ferulic acid has been detected in biofluids Metabolism

  Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
5-caffeoylquinic acid Not applicable 2 g/day 7 days 20 71 µmol/24h after 1 weeks OLTHOF 2003
almond skin extract capsules Food administered
 10 capsules Single dose 2 URPI-SARDA 2009_02
black tea solids Food administered
 4 g/day 7 days 20 34 µmol/24h after 1 weeks OLTHOF 2003
citric acid in water Not applicable 0.5 g/day 7 days 20 26 µmol/24h after 1 weeks OLTHOF 2003
cocoa powder in skimmed milk Food administered
Generic food 		40 g/day 4 weeks 42 4.28 µmol after 24 hours 0.21 µmol/L after 24 hours URPI-SARDA 2009_03
cocoa powder in water Food administered
Generic food 		40 g Single dose 21 10.52 nmol/mg creatinine after 24 hours URPI-SARDA 2009_01
cocoa powder in water Food administered
Generic food 		40 g Single dose 21 Graph URPI-SARDA 2010
cocoa powder in whole milk Food administered
Generic food 		40 g Single dose 21 Graph URPI-SARDA 2010
dark chocolate Generic food 80 g Single dose 11 Graph RIOS 2003
epicatechin Not applicable 200 mg Single dose 12 Graph LOKE 2009
epigallocatechin gallate Not applicable 200 mg Single dose 12 Graph LOKE 2009
instant coffee in hot water Food administered
 4 g Single dose 1 1 0.12 Graph GUY 2009
one tablet of perilla extract Food administered
 1 tablet Single dose 6 2.86 Graph BABA 2005
quercetin Not applicable 200 mg Single dose 12 Graph Graph LOKE 2009
quercetin 3-O-rutinoside Not applicable 440 mg/day 7 days 20 27 µmol/24h after 1 weeks OLTHOF 2003
rat studies
5-caffeoylquinic acid Not applicable 250 µmol/day 8 days 8 Graph 0.4 µmol/L after 8 days GONTHIER 2003_01
caffeic acid Not applicable 250 µmol/day 8 days 8 14.5 µmol after 8 days 7.3 µmol/L after 8 days GONTHIER 2003_01
catechin Not applicable 0.12 g/100 g bw Single dose 8 163.2 µg after 8 days GONTHIER 2003_03
catechin Not applicable 0.1 % of diet 5 days 5 0.3 µmol after 5 days GONTHIER 2003_02
cranberry powder diet Food administered
 6.6 mg/kg bw Single dose 10 2.4 µg/mg creatinine after 30 days PRIOR 2010
ferulic acid Not applicable 5.15 mg/kg bw Single dose 33 43.4 Graph 0.5 1.68 Graph RONDINI 2002
instant coffee powder in water Food administered
 4 g Single dose 5 Graph RECHNER 2001
natural cocoa powder Food administered
 4.8 g/kg bw/day 2 weeks 7 3.48 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
rosmarinic acid in deoinized water Not applicable 50 mg/kg bw Single dose 5 1.7 Graph BABA 2004
wine powder Food administered
 0.5 g/100 g bw Single dose 8 231.2 µg after 8 days GONTHIER 2003_03
  Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
blackcurrant juice Food administered
 330 mL Single dose 10 Graph Graph RECHNER 2002_02
green coffee bean extract drink Food administered
 250 mL Single dose 5 Graph MATSUI 2007
Ocean Spray cranberry juice cocktail Food administered
 1800 mL Single dose 1 Graph ZHANG 2004_01
one tablet of perilla extract Food administered
 1 tablet Single dose 6 0.5 0.36 BABA 2005
rat studies
caffeic acid Not applicable 40 mg/kg bw Single dose 8 Detected (unquantified) ZHANG 2008_02
cranberry powder diet Food administered
 6.6 mg/kg bw Single dose 10 0.11 µg/mg creatinine after 30 days PRIOR 2010
dihydrocaffeic acid Not applicable 100 µmol/kg bw Single dose 0 Detected (unquantified) Detected (unquantified) POQUET 2008
ferulic acid Not applicable 40 mg/kg bw Single dose 8 Detected (unquantified) Detected (unquantified) ZHANG 2008_02
ferulic acid Not applicable 0.42 % of diet 0 hours 5 Detected (unquantified) FARDET 2008_02
raspberry juice Food administered
Generic food 		2.77 mL Single dose 24 Graph BORGES 2007